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hepatopulmonary syndrome |
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hepatopulmonary syndrome, arterial hypoxemia caused by pulmonary vasodilation in conjunction with chronic liver disease, usually occurring as a result of portal hypertension in cirrhosis. hepatopulmonary syndrome A condition in which hypoxemia due to intrapulmonary shunting and/or a V/Q mismatch develops in a Pt with liver cirrhosis; usually there is no apparent parenchymal lung disease, but Pts may have orthodeoxia, an
unusual finding of ↑ hypoxemia with a change from the supine to the erect position; the pathogenesis of HPS is uncertain but may be due to an ↑ production of endogenous nitric oxide; shunting of HPS may respond to IV methylene blue How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Hepatopulmonary Syndrome (HPS) is considered when patients have a triad of liver disease, increased arterial-alveolar gradient while breathing on room air, and evidence of intrapulmonary vascular abnormalities. The third patient had hepatopulmonary syndrome and had undergone transjugular intrahepatic portosystemic shunting. 37) The hepatopulmonary syndrome (HPS) is a triad of liver disease, increased alveolar-arterial oxygen gradient, and intrapulmonary vascular dilatations. |
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