2) On ultrasound, geographic areas of decreased echogenicity with preservation of portal tracts are early signs of hepatic ischemia
and may resolve completely or progress to true infarction.
The pathophysiology results from hepatic ischemia
due to intrahepatic obstruction from sickling in the sinusoids (1, 2).
Human activated protein C attenuates both hepatic and renal injury caused by hepatic ischemia
and reperfusion injury in mice.
Hepatic congestion occurs during occlusion over the hepatic veins, but is relieved by repositioning, and the risk of hepatic ischemia
, that is otherwise associated with IVC thrombectomy, is avoided.
Hepatic ischemia which is a frequent problem encountered in clinical conditions such as liver transplantations, liver deficiency and liver surgery results in functional and structural defects in hepato-cytes (Debonera et al.
30 min hepatic ischemia applied to rats were reported to decrease liver GSH level and increased the MDA level (Koken and Inal, 1999).
Role of hepatocyte growth factor in hepatic ischemia and reperfusion injury.
Analysis of all postoperative measurements showed that cholesterol was correlated directly with the preoperative concentration, albumin, total protein, fibrinogen, urate, alkaline phosphatase and y-glutamyltranspeptidase (accounting for cholestasis), prothrombin activity, hematocrit, hemoglobin, and red blood cell and platelet counts, and inversely with total and indirect bilirubin, white blood cell count, number of resected segments, and duration of operation and hepatic ischemia
The effect of L- arginine therapy on hepatic ischemia
has not yet been completely elucidated.