hepatic insufficiency


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Related to hepatic insufficiency: renal insufficiency, liver insufficiency

he·pa·tic in·suf·fi·cien·cy

defective functional activity of the liver cells.

hepatic insufficiency

a failure or partial failure of normal liver function.

he·pa·tic in·suf·fi·cien·cy

(he-patik in-sŭ-fishĕn-sē)
Defective functional activity of the liver cells.

he·pa·tic in·suf·fi·cien·cy

(he-patik in-sŭ-fishĕn-sē)
Defective functional activity of the liver cells.

insufficiency

inability to perform properly an allotted function.

adrenal insufficiency
hypoadrenalism.
aortic insufficiency
inadequacy of the aortic valve, permitting blood to flow back into the left ventricle of the heart.
cardiac insufficiency
inability of the heart to perform its function properly; heart failure.
coronary insufficiency
decreased supply of blood to the myocardium resulting from constriction or obstruction of the coronary arteries, but not accompanied by necrosis of the myocardial cells. Called also ischemic myocardial necrosis.
hepatic insufficiency
inadequate liver function, short of hepatic failure.
ileocecal insufficiency
inability of the ileocecal valve to prevent backflow of contents from the cecum into the ileum.
pulmonary insufficiency
insufficiency of the pulmonary valve, permitting blood to flow into the right ventricle of the heart.
respiratory insufficiency
a condition in which respiratory function is inadequate to meet the body's needs when increased physical activity places extra demands on it. See also respiratory insufficiency.
thyroid insufficiency
hypothyroidism.
valvular insufficiency
failure of a cardiac valve to close perfectly, causing the blood to flow back through the orifice (valvular regurgitation); named, according to the valve affected, aortic, mitral, pulmonary or tricuspid insufficiency.
velopharyngeal insufficiency
failure of velopharyngeal closure due to cleft palate, muscular dysfunction, etc., resulting in defective swallowing with regurgitation through the nose.
venous insufficiency
inadequacy of the venous valves with impairment of venous drainage, resulting in edema.
References in periodicals archive ?
It was noted early in the implementation of the DSRS that patients with this procedure retained a superior ability to handle gastrointestinal protein and ammonia loads, and it is still believed that the relatively high hepatic portal perfusion following DSRS contributes to the lower rates of hepatic insufficiency and encephalopathy(9).
Special warnings and precautions: Lactic acidosis can occur due to metformin accumulation or whenever any condition associated with hypoxia, hepatic insufficiency, or poorly controlled diabetes occurs.
Factors triggering simvastatin myopathy Factor NP CK Myalgia Weakness Drugs Colchicine 1 + + Fusidic acid 1 + Verapamil/cyclosporine 1 + Cortisone azathioprine, cyclosporine 1 + Amiodarone 2 + + + Nefazodone 1 + Danazol/renal failure 1 + Clarithromycin 2 + + + Itraconazole/cyclosporine 1 + Itraconazole/gemfibrozil, cyclosporine 1 + Tacrolimus/fusidic acid 1 + Diltiazem 1 + Fibrates 1 + Fluconazole 1 + + Nelfinavir 1 + + Ritonavir 1 + ng ng Indomethacin/renal failure 1 + ng ng Troglitazone 1 + Conditions Diabetes 1 + + Renal insufficiency ng + Hepatic insufficiency ng + Hypothyroidism ng + Muscle activity ng + NP, Number of patients; CK, creatine kinase; ng, not given.
Use is not recommended in patients with moderate to severe hepatic insufficiency because no studies have been conducted in this patient population.
The transplant operation for Kyoko Kobayashi, who suffers from hepatic insufficiency caused by stenosis of bile duct, was carried out after a donor with matching tissue was found.
Due to the unknown effects of increased exposure to ZETIA in patients with moderate or severe hepatic insufficiency, ZETIA is not recommended in these patients.
Administration of GEMZAR in patients with concurrent liver metastases or a preexisting medical history of hepatitis, alcoholism, or liver cirrhosis can lead to exacerbation of hepatic insufficiency.
After liver resection, a degree of hepatic insufficiency can result in reduced levels of procoagulant and anticoagulant factors normally synthesised in the liver.
5% of these patients will experience severe hepatitis due to acute hepatocellular necrosis or hypofunction, which results in hepatic insufficiency and hepatic failure.
Modest increases in caspofungin AUC (19% to 55%) have been observed in single-dose and multipledose studies in patients with mild hepatic insufficiency (Child-Pugh score, 5-6).
Potassium excretion is increased initially upon administration of methazolamide and in patients with cirrhosis or hepatic insufficiency could precipitate a hepatic coma.
The liver metabolizes almost 100% of diclofenac, and there is insufficient information to support dosing recommendations in patients with hepatic insufficiency.