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hepatic insufficiency |
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hepatic insufficiency, a failure or partial failure of normal liver function. insufficiency inability to perform properly an allotted function. adrenal insufficiency hypoadrenalism. aortic insufficiency inadequacy of the aortic valve, permitting blood to flow back into the left ventricle of the heart. cardiac insufficiency inability of the heart to perform its function properly; heart failure. coronary insufficiency decreased supply of blood to the myocardium resulting from constriction or obstruction of the coronary arteries, but not accompanied by necrosis of the myocardial cells. Called also ischemic myocardial necrosis. hepatic insufficiency inadequate liver function, short of hepatic failure. ileocecal insufficiency inability of the ileocecal valve to prevent backflow of contents from the cecum into the ileum. pulmonary insufficiency insufficiency of the pulmonary valve, permitting blood to flow into the right ventricle of the heart. respiratory insufficiency a condition in which respiratory function is inadequate to meet the body's needs when increased physical activity places extra demands on it. See also respiratory insufficiency. thyroid insufficiency hypothyroidism. valvular insufficiency failure of a cardiac valve to close perfectly, causing the blood to flow back through the orifice (valvular regurgitation); named, according to the valve affected, aortic, mitral, pulmonary or tricuspid insufficiency. velopharyngeal insufficiency failure of velopharyngeal closure due to cleft palate, muscular dysfunction, etc., resulting in defective swallowing with regurgitation through the nose. venous insufficiency inadequacy of the venous valves with impairment of venous drainage, resulting in edema. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| ? Mentioned in | ? References in periodicals archive | |
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No dosage adjustment is needed for patients with mild to moderate hepatic insufficiency or in patients with mild renal insufficiency (CrCl [greater than or equal to]50 mL/min). Hepatic Insufficiency Plasma concentrations of caspofungin after a single 70-mg dose in patients with mild hepatic insufficiency (Child-Pugh score 5 to 6) were increased by approximately 55% in AUC compared to healthy control subjects. No dosage adjustment is needed for patients with mild to moderate hepatic insufficiency or in patients with mild renal insufficiency (CrCl [greater than or equal to]50 mL/min). |
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