heparin-binding protein


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AZU1

A gene on chromosome 19q13.3 that encodes an azurophil granule protein of the serine protease family (but is not itself a serine protease), which has monocyte chemotactic and antibacterial activity, and acts as an important multifunctional inflammatory mediator. The genes encoding the AZU1 protein product, neutrophil elastase 2 and proteinase 3, are in a cluster at chromosome 19pter, and all three are expressed and packaged together into azurophil granules during neutrophil differentiation.

heparin-binding protein

A proinflammatory, antimicrobial peptide released by neutrophils. It increases the permeability of blood vessels. It is found in high concentrations in plasma of patients with septic shock.
See also: protein
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Perhaps the most significant discovery has been the participation of heparin-binding proteins (HBPs) in the sperm capacitation (THERIEN et al.
Heparin-binding proteins of seminal plasma in Nellore bulls/Proteinas ligadoras a heparina do plasma seminal em touros Nelore
Heparin-binding proteins from seminal plasma bind to bovine spermatozoa and modulate capacitation by heparin.
Seminal plasma heparin binding proteins improve semen quality by reducing oxidative stress during cryopreservation of cattle bull semen
d] of -16 pmol/L, a photo cross-linking yield of 50%, and specific binding to bFGF that is more than three orders of magnitude higher than binding to other heparin-binding proteins, such as vascular endothelial growth factor and platelet-derived growth factor (13).
Photoaptamer technology: development of multiplexed microarray protein assays

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