Coagulopathic bleeding can be due to the same factors that complicate bleeding in the intraoperative setting, for example, dilution of clotting factors, heparin rebound
effect, and pathologic clot lysis.
Persistent concentrations of circulating heparin, resulting from inadequate neutralization [85, 86] or heparin rebound [86, 87], can contribute to MVB after CPB.
Heparin management protocol for cardiopulmonary bypass influences postoperative heparin rebound but not bleeding.
Heparin-protamine complexes in the production of heparin rebound and other complications of extracorporeal bypass procedures.
Management of postoperative heparin rebound following cardiopulmonary bypass.
Identification of heparin rebound by measurement of whole blood thrombin time in CABG patients [Abstract].