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hemosiderin

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hemosiderin /he·mo·sid·er·in/ (he″mo-sid´er-in) an insoluble form of tissue storage iron, visible microscopically both with and without the use of special stains.
he·mo·sid·er·in (hm-sdr-n)
n.
An insoluble protein that contains iron and that is produced by phagocytic digestion of hematin and found as granules in most tissues, especially in the liver.

hemosiderin
[hē′mōsid′ərin]
Etymology: Gk, haima + sideros, iron
an iron-rich pigment that is a product of red cell hemolysis. Iron is often stored in this form. Also spelled haemosiderin.

hemosiderin (hē´mōsid´rin),
n an intracellular storage form of iron; the granules consist of an ill-defined complex of ferric hydroxides, polysaccharides, and proteins having an iron content of approximately 33% by weight. It appears as a dark yellow-brown pigment.

hemosiderin
an insoluble form of intracellular storage iron, visible microscopically both with and without the use of special stains.


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Foam cells with vacuolated cytoplasm may be present, and they often have pigmented cytoplasmic granules containing hemosiderin.
Dramatic decreases in bone marrow hemosiderin levels have been reported in some distance runners.
These observations included the presence of pale, shiny, skin, thickened nails, little hair growth, cool skin temperature, weak or absent foot pulses, and the presence of varicosities or visual identification of skin stained with dark brown hemosiderin pigment, or bilateral limb swelling or lymphedema.
 
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