Hemorrhagic transformation (HT), is a natural phenomena in the ischemic stroke population.
5,12] Hemorrhagic transformation can be diagnosed by CT scan within 7-10 days following the stroke (Fig 2).
In patients with large infarcts, the initiation of warfarin therapy should be delayed for 2 weeks due to the potential risk of hemorrhagic transformation
In addition, plasma concentrations of MMP-9 were found to predict hemorrhagic transformation
in patients with acute ischemic stroke (11).
The investigators noted that it is unclear whether evidence of hemorrhagic transformation
on MRI conveys a higher risk of symptomatic hemorrhage with thrombolytic treatment.
3) indicated that twenty cases of non-hemorrhagic stroke or transient ischemic attack have been treated with thrombolysis, with only one hemorrhagic transformation
A sample of topics includes venous steal in cerebral ischemia, systemic hemodynamic therapies for acute ischemic stroke, causes and treatment of hemorrhagic transformation
, and translational hurdles in novel stroke therapies.
MMP activation plays a crucial role in the pathogenesis of brain edema and hemorrhagic transformation
after ischemic stroke.
1-cm high-density mass suggesting hemorrhagic transformation
was seen within the region of the right caudate, encroaching on the right lateral ventricle.
Minocycline treatment in this study did not correlate with a lower risk of death, myocardial infarction, recurrent strokes, or hemorrhagic transformation
Augmentation of blood pressure in acute stroke may theoretically diminish cerebral ischemia, yet hypertension may also aggravate cerebral edema or precipitate hemorrhagic transformation
The five deaths comprised three patients who died from hemorrhagic transformations
and two who died from large ischemic infarctions.