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hemolytic transfusion reaction |
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hemolytic transfusion reaction
Transfusion medicine A therapy-related event mediated by 2 different mechanisms: 1. Intravascular hemolysis mediated by complement-fixing antibodies, 2. Extravascular hemolysis mediated by noncomplement-fixing
antibodies Clinical Fever, chills, pain at infusion site, intense back pain, hypotension, sense of impending doom, chest tightness, acute dyspnea, brochospasm, anaphylaxis, hyperbilirubinemia, hemoglobinuria, DIC with fibrinolysis
Management Stop transfusion, treat shock–vasopressors, IV fluids, cortiocosteroids, maintain high fluid throughput, monitor anemia, transfuse with compatible blood How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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