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hemolysin

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hemolysin /he·mol·y·sin/ (he-mol´ĭ-sin) a substance that liberates hemoglobin from erythrocytes by interrupting their structural integrity.
he·mol·y·sin (h-ml-sn, hm-l-)
n.
An agent or a substance, such as an antibody or a bacterial toxin, that causes the destruction of red blood cells, thereby liberating hemoglobin. Also called erythrocytolysin, erythrolysin.

hemolysin
[himol′əsin]
Etymology: Gk, haima + lysis, loosening
any one of the numerous substances that lyse or dissolve red blood cells. Hemolysins are produced by bacterial strains, including staphylococci and streptococci, and are contained in venoms and vegetables. Bacterial hemolysins are divided into those that are filterable and those that cluster around the bacterial colony on a culture medium containing red blood cells. Hemolysins appear to aid the invasive power of bacteria. Also spelled haemolysin. See also hemoglobin, hemolysis.

hemolysin (hēmol´isin),
n an antibody that causes hemolysis of red blood cells in vitro.

hemolysin
a substance that liberates hemoglobin from erythrocytes by interrupting their structural integrity.


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suis ST-7 expressed the proposed virulence markers muramidase-released protein (MRP), extracellular protein factor (EF), and hemolysin (named suilysin) (9-11) and was markedly more cytototoxic to human peripheral blood mononuclear cells (PBMC) than a representative ST-1 strain.
But for something as complex as hemolysin, I think Bayley's come up with a fabulous experimental system.
Strains that produce the thermostable direct hemolysin or the thermostable direct hemolysin-related hemolysin, which are encoded by tdh and trh genes, respectively, are considered pathogenic.
 
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