hemodilution


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hemodilution

 [he″mo-dĭ-loo´shun]
increase in the fluid content of blood, resulting in diminution of the concentration of formed elements.

he·mo·di·lu·tion

(hē'mō-di-lū'shŭn),
Increase in the volume of plasma in relation to red blood cells; reduced concentration of red blood cells in the circulation.

hemodilution

/he·mo·di·lu·tion/ (-di-loo´shun) increase in fluid content of blood, resulting in lowered concentration of formed elements.

hemodilution

[-dilo̅o̅′shən]
Etymology: Gk, haima, blood; L, diluare, to wash away
a condition in which the concentration of erythrocytes or other blood elements is lowered, usually resulting from an increase in plasma volume, often secondary to the use of plasma. Also spelled haemodilution.

hemodilution

Cardiovascular surgery A technique used during cardiopulmonary bypass to ↓ risk of intraoperative thrombosis diluting the blood with crystalloids, ↓ hematocrit to ≤ 0.25-0.30 Transfusion medicine The removal of blood from a Pt at induction of anesthesia while replacing the volume with crystalloids–eg, saline or lactated Ringer's solution, or with colloids–eg, albumin, hydroxyethyl starch, dextrans, or purified protein fractions, or a combination of the 2. See Albumin, Dextrans, Hydroxyethyl starch, Intraoperative hemodilution, Purified protein fractions, Surgical blood management.

he·mo·di·lu·tion

(hē'mō-di-lū'shŭn)
Increase in the volume of plasma in relation to red blood cells; reduced concentration of red blood cells in the circulation.
Synonym(s): haemodilution.

hemodilution

increase in the fluid content of blood, resulting in diminution of the concentration of formed elements.
References in periodicals archive ?
4) proposed the standard use of this trigger for anemic shock patients and much later Stheling and Zauder (5) provided the scientific basis for these numbers by showing in hemorheology experiments that a Ht of 30% provided the peak oxygen delivery value during hemodilution after which the oxygen carrying capacity of blood declines.
Hemodilution due to right-sided heart failure, although not true anemia, is associated with adverse outcomes.
A negative correlation between air temperature, PCV, number of RBCs and HB concentration was reported [20], while in the present study a negative relationship was also noted between these hematological constituents and THI, which can be attributed to the hemodilution effect [28].
The primary objective was to assess the accuracy of cPDE in predicting the hemodilution responsiveness using the receiver operating characteristic (ROC) curve and gray zone approaches [6].
On the other hand, during CPB patient's body undergoes a serial sequence of events (hypothermia, hemodilution, arrest, ischemia, reperfusion, and extracorporeal circulation) which induce cell damage due to ATP breakdown and depletion of the naturally occurring defense mechanisms against free radical injury and endothelial function impairment, all contributing to the development of organ dysfunction [11].
A study examining standardized blunt abdominal trauma with induction of hypothermia and hemodilution with subsequent administration of 4F-PCC (Cofact) at 35 U/kg demonstrated higher fibrinogen levels, higher hemoglobin concentration, higher platelet counts, and decreased PT values compared to a control group.
3) Other notable conditions that can affect the PSA concentration included metabolic syndrome (MS) or obesity, which has been associated with decreased serum PSA possibly due to hemodilution.
However, several recent studies suggest an increased risk of renal injury due to hemodilution with hematocrit levels below 25%.
Due to hemodilution and active transport of Vitamin C to the fetus plasma (which increases throughout pregnancy), Vitamin C concentration decreases progressively during pregnancy regardless of supplementation15,16.
Acute normovolemic hemodilution (ANH): Haemodilution is defined as the artificial reduction of the erythrocyte count in the blood by dilution with crystalline or colloidal fluids.
Hemodilution occurs primarily as a result of the initiation of cardiopulmonary bypass (CPB) due to replacing a portion of the patient's blood volume with the priming solution (crystalloids and colloids) in the CPB circuit.