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hemodilution

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hemodilution /he·mo·di·lu·tion/ (-di-loo´shun) increase in fluid content of blood, resulting in lowered concentration of formed elements.
he·mo·di·lu·tion (hm-d-lshn, -d-)
n.
An increase in the volume of plasma, resulting in a reduced concentration of red blood cells in blood.

hemodilution
[-dilo̅o̅′shən]
Etymology: Gk, haima, blood; L, diluare, to wash away
a condition in which the concentration of erythrocytes or other blood elements is lowered, usually resulting from an increase in plasma volume. Also spelled haemodilution.

hemodilution
increase in the fluid content of blood, resulting in diminution of the concentration of formed elements.

hemodilution
Cardiovascular surgery A technique used during cardiopulmonary bypass to ↓ risk of intraoperative thrombosis diluting the blood with crystalloids, ↓ hematocrit to ≤ 0.25-0.30 Transfusion medicine The removal of blood from a Pt at induction of anesthesia while replacing the volume with crystalloids–eg, saline or lactated Ringer's solution, or with colloids–eg, albumin, hydroxyethyl starch, dextrans, or purified protein fractions, or a combination of the 2. See Albumin, Dextrans, Hydroxyethyl starch, Intraoperative hemodilution, Purified protein fractions, Surgical blood management.


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Low blood lead concentrations during the first half of pregnancy have been attributed to hemodilution (Rothenberg et al.
The proposed study protocol was developed utilizing data from a successful international Phase 3 study with 492 surgical patients, which demonstrated that Oxygent and acute normovolemic hemodilution treatment provided a statistically significant reduction and avoidance of donor blood usage.
The panel says other safe alternatives, such as intraoperative blood salvage (collecting blood from a patient during an operation for subsequent use) and hemodilution (removing blood and substituting other fluids to keep blood volume up) are useful in selected cases, while some of the more innovative approaches, including artificial blood, remain experimental.
 
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