helmet cells

helmet cells

fragmented red blood cells that appear "scooped out" so they resemble helmets. They are found in patients with micro-angiopathic hemolytic anemia and thrombotic thrombocytopenic purpura. Helmet cells can also be seen in blood samples of people with prosthetic heart valves and in individuals with unstable hemoglobin conditions that produce Heinz bodies.
References in periodicals archive ?
Hemolytic uremic syndrome (HUS) is defined by a triad of microangiopathic hemolytic anemia (characterized by schistocytes and helmet cells, as shown in Fig.
The peripheral blood smear can show up to 10% schistocytes, along with helmet cells, which are produced due to damage of the endothelial layer of small vessels, resulting in fibrin deposition and platelet aggregation.
Microangiopathic hemolysis ([greater than or equal to]1% schistocytes plus helmet cells and the presence of any number of spherocytes)