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helicase

   Also found in: Encyclopedia, Wikipedia 0.01 sec.
helicase
an enzyme involved in DNA replication, responsible for unwinding the double helix.


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Srs2 is a helicase molecule - a motor protein that's able to walk or slide along a strand of DNA and remove other proteins from DNA or separate the two strands of the twisted double helix.
V1213A in ORF1 corresponds to V239A of the helicase domain, and its surrounding sequences were well conserved in HEV isolates of genotypes 3 and 4 (online Appendix Figure, available from www.
To date, research has focused on the envelope glycoprotein, the NS3 protease and helicase, and the NS5 methytransferase and RNA-dependent RNA polymerase (RdRp) as targets for antiviral therapy.
 
 
 
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