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hedgehog proteins

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hedgehog proteins
a family of secreted signaling proteins that are involved in the embryogenesis; mutations in these proteins are implicated in some birth defects and cancers.


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Treating blind fish embryos with a drug that inhibits both the hedgehog proteins partially restored eye development.
These additional Hedgehog-based programs are as follows: Systemically administered small molecule Hedgehog agonist for the treatment of neurological disorders (in collaboration with Wyeth): In January 2004, Curis licensed its Hedgehog proteins and small molecule Hedgehog pathway agonists to Wyeth for therapeutic applications in the treatment of neurological diseases and other disorders.
patent 6,994,990, entitled "Active Modified Hedgehog Proteins.
 
 
 
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