By analysing adjusted population attributable fractions, they found that most attributable cases of moderate-to-severe diarrhoea were due to four pathogens: rotavirus, Cryptosporidium, enterotoxigenic Escherichia coli producing heat-stable toxin
(ST-ETEC; with or without co-expression of heat-labile enterotoxin), and Shigella.
The diarrhea is mediated by 1 or 2 plasmid-encoded enterotoxins; the heat-stable toxin
(ST) and/or the heat-labile toxin (LT) (1).
b) NM, nonmotile; LT, heat-labile toxin; ST, heat-stable toxin
Heat-stable toxin (ST) was determined in parallel in the same cultures by an inhibition-G[M.
Monoclonal antibodies against Escherichia coli heat-stable toxin (Sta) and their use in diagnostic ST ganglioside [GM.
b) EAST, heat-stable toxin
1 of EAEC; E-hly, EHEC hemolysin; AA, aggregative adherence; Afa, afimbrial adhesin.
These toxins, which affect eukaryotic cells by a variety of means, include Staphylococcus aureus [Alpha]-toxin, Shiga toxin, cytotoxic necrotizing factor type 1, Escherichia coil heat-stable toxin, botulinum and tetanus neurotoxins, and S.
coli heat-stable toxin (ST), botulinum and tetanus neurotoxins, and toxic-shock syndrome toxin (TSST)produced by S.
This is untrue, as heat-stable toxins
can remain in the food even after it has been cooked.
Sue Gilbert, a scientist involved in the experiments, said, "The types of chilled raw meat used in these experiments would be cooked before being eaten, thus destroying most, if not all, the bacteria present, although spores and heat-stable toxins
And some studies have shown evidence of biofilms forming in steam autoclaves and emitting heat-stable toxins