Antibodies to heat-labile
Escherichia coli enterotoxin in Apaches in Whiteriver, Arizona.
Intercell's VE Patch contains the heat-labile
enterotoxin (LT) from E.
Measured concentrations ranged from 91% to 107% of untreated values for electrolytes, metabolites, enzymes, proteins, and hormones (Table 1), offering a virus inactivation procedure for heat-labile
analytes such as creatine kinase, myoglobin, alanine aminotransferase, [gamma]-glutamyl transferase, lactate dehydrogenase, alkaline phosphatase, and free thyroxine.
People can be allergic to heat-labile
egg proteins in raw eggs that get neutralized when cooked.
coli (ETEC) causes travelers diarrhea, is rare in the United States, and produces heat-stable or heat-labile
Aphios' virus inactivation process can be applied to immunoglobulins and wound healing biotherapeutics, human plasma used for blood transfusions, bone graft materials and other implantables, heat-labile
and sensitive medical instrumentation, xenotransplantation products, animal sera used in the biotechnology industry, and recombinant therapeutics from mammalian cell culture and transgenic animals where a virus inactivation step is essential and necessary for the manufacture of safe products.
The A subunit of CT has over 82 per cent sequence identity with the Escherichia coli heat-labile
enterotoxin (LT), while the B subunits of the former shares over 83 per cent sequence identity with the latter (10).
The diarrhea is mediated by 1 or 2 plasmid-encoded enterotoxins; the heat-stable toxin (ST) and/or the heat-labile
toxin (LT) (1).
ETEC causes illness through the toxins it produces, including one known as heat-labile
toxin or LT.
Cross-protection by B subunit-whole cell cholera vaccine against diarrhea associated with heat-labile
toxin-producing enterotoxigenic Escherichia coli: results of a large-scale field trial.
An enterotoxigenic Escherichia coli (ETEC) strain, H10407, producing heat-labile
toxin (LT) served as a positive control for enterotoxin production.
The best protection was reported for mice vaccinated by the intranasal route with an M2e-hepatitis B core fusion protein construct and detoxified heat-labile
Escherichia coli enterotoxin adjuvant; almost none of these mice died after a virus challenge that killed 90% of control mice (21).