hapten

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hapten

 [hap´ten]
a small molecule, not antigenic by itself, that can react with specific antibodies and elicit the formation of such antibodies when conjugated to a larger antigenic molecule, usually a protein, called in this context the carrier. Antibody production involves activation of B lymphocytes by the hapten and helper T cells by the carrier.

hap·ten

(hap'-ten),
A molecule that is incapable, by itself, of causing a cell-mediated or humoral immune response but can, however, combine with a larger antigenic molecule called a carrier. A hapten-carrier complex can stimulate antibody production and reactive T-cells.
See also: hapten inhibition of precipitation.
[G. haptō, to fasten, bind]

hapten

/hap·ten/ (hap´ten) partial antigen; a specific nonprotein substance which does not itself elicit antibody formation but does elicit the immune response when coupled with a carrier protein.hapten´ic

hapten

(hăp′tĕn′) also

haptene

(-tēn′)
n.
A small molecule that reacts with a specific antibody but cannot induce the formation of antibodies unless bound to a carrier protein or other large antigenic molecule.

hap·ten′ic adj.

hapten

[hap′tən]
Etymology: Gk, haptein, to grasp
a small molecule that acts as an antigen by combining with particular bonding sites on an antibody. By itself it cannot induce an immune response, but when bonded to a carrier protein may cause an immune response.

hap·ten

(hap'tĕn)
A molecule that is incapable, alone, of causing the production of antibodies but can, however, combine with a larger antigenic molecule called a carrier.
Synonym(s): incomplete antigen, partial antigen.
[G. haptō, to fasten, + -en, noun suffix]

hapten

An incomplete antigen that cannot, by itself, promote antibody formation but that can do so when conjugated to a protein. Most haptens are organic substances of low molecular weight. From the Greek haptein , to fasten.

hapten

a substance that is able to combine with specific antibodies but does not produce them unless attached to a large CARRIER MOLECULE.

hap·ten

(hap'tĕn)
A molecule that is incapable, alone, of causing the production of antibodies but can, however, combine with a larger antigenic molecule called a carrier.
Synonym(s): incomplete antigen, partial antigen.
[G. haptō, to fasten, + -en, noun suffix]

hapten (hap´tən),

n a nonproteinaceous substance that acts as an antigen by combining with particular bonding sites on an antibody. Unlike a true antigen, it does not induce the formation of antibodies. A hapten bonded to a carrier protein may induce an immune response. Also called
haptene.

hapten, haptene

a small-molecular-weight either inorganic or organic molecule that alone is not antigenic but which when linked to a carrier protein, e.g. albumin, is antigenic; the antibody so produced will react with the hapten alone.