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hapten |
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hapten /hap·ten/ (hap´ten) partial antigen; a specific nonprotein substance which does not itself elicit antibody formation but does elicit the immune response when coupled with a carrier protein.hapten´ic
hapten [hap′tən] Etymology: Gk, haptein, to grasp a nonproteinaceous substance that acts as an antigen by combining with particular bonding sites on an antibody. Unlike a true antigen, it does not induce the formation of antibodies. A hapten bonded to a carrier protein may cause an immune response. Also called haptene [hap′tēn] . hapten (hap´t n a nonproteinaceous substance that acts as an antigen by combining with particular bonding sites on an antibody. Unlike a true antigen, it does not induce the formation of antibodies. A hapten bonded to a carrier protein may induce an immune response. Also called haptene. hapten, haptene a small-molecular-weight either inorganic or organic molecule that alone is not antigenic but which when linked to a carrier protein, e.g. albumin, is antigenic; the antibody so produced will react with the hapten alone. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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The mature antibody binds hapten 30,000 times better than its immature version. This hapten modification allows the tumor cells to stimulate a T cell-based immune response to a patients own tumor cells. Formaldehyde may cause an immune response by forming a hapten, a complex of a protein and a low-molecular-weight compound, which can induce an IgE response, although this is uncommon (Rutchik 1999). |
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