haplotype


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

haplotype

 [hap´lo-tīp]
1. a set of alleles of a group of closely linked genes, such as the HLA complex, which are usually inherited as a unit, an individual inheriting a complete haplotype from each parent.
2. the genetic constitution of an individual at a set of linked genes.

hap·lo·type

(hap'lō-tīp),
1. The genetic constitution of an individual with respect to one member of a pair of allelic genes; individuals are of the same haplotype (but of different genotypes) if alike with respect to one allele of a pair but different with respect to the other allele of a pair.
2. In immunogenetics, that portion of the phenotype determined by a set of closely linked genes inherited from one parent (that is, genes located on one of the pair of chromosomes).
[haplo- + G. typos, impression, model]

haplotype

/hap·lo·type/ (-tīp) the group of alleles of linked genes, e.g., the HLA complex, contributed by either parent; the haploid genetic constitution contributed by either parent.

haplotype

(hăp′lə-tīp′)
n.
A set of alleles of different genes that are closely linked on one chromosome and are usually inherited as a unit.

hap·lo·type

(hap'lō-tīp)
1. The genetic constitution of an individual with respect to one member of a pair of allelic genes; individuals are of the same haplotype (but of different genotypes) if alike with respect to one allele of a pair but different with respect to the other allele of a pair.
2. immunogenetics That portion of the phenotype determined by a set of closely linked genes inherited from one parent (i.e., genes located on one of the pair of chromosomes). The human major histocompatability complex comprises 4 recognized loci (A, B, C, and D) for which there are more than 50 alleles. Similarly, the allotypic markers (antigens) of the immunoglobulin subclasses IgG1, IgG2, IgG3, and IgA2 occur in combinations and are inherited as units almost always unchanged in transmission; the alleles that control these various haploptypes are not linked to those controlling the antigens of the κ type L chains.
[haplo- + G. typos, impression, model]

haplotype

The entire set of allelic variants that may be found at any particular genetic location.

haplotype

see HLA SYSTEM.

Haplotype

A set of alleles (an alternative form of a gene that can occupy a particular place on a chromosome) of a group of closely linked genes which are usually inherited as a unit.

haplotype

the group of alleles of linked genes contributed by either parent; the haploid genetic constitution contributed by either parent.
References in periodicals archive ?
The Y-SNP haplotype diversity and nucleotide diversity for each breeds were calculated using software DnaSPv5 (Librado and Rozas, 2009) without considering locus Y-45288, because the DnaSPv5 software cannot distinguish deletion.
In contrast, maximum parsimony supported monophyly for the Yaqui catfish (98% bootstrap support), but did not resolve relationships of the three Sinaloa catfish haplotypes.
In Ethiopia, both SGEAA and SGEGA alleles were associated with haplotype 4 (121-114-98), indicating a shared ancestry that has evolved independently from SGEAA and SGEGA alleles from Uganda and Tanzania.
Haplotype and nucleotide diversity was slightly greater in Haplogroup 2 (Hd = 0.
Y-chromosome variation was analysed at the haplogroup level defined by bi-allelic polymorphisms only, and at the haplotype level defined by both bi-allelic and STR markers.
sikamea distribution is likely somewhere along the central coast of China, possibly in the Zhoushan and Fenghua areas, if the abundance and high haplotype diversity there are good indications.
The estimated differences in mean %MMA decreased somewhat after adjusting for AS3MT haplotype (model 2, Table 3).
demonstrated the ability to construct a fetal genomic map by combining maternal plasma DNA-sequencing data, paternal genotype information, and maternal haplotype information.
Genomic DNA was extracted and the frequency of the EPCR gene A3 haplotype 1651 C-G was screened via PCR using the primers 5'-GCTGAAATTTTGTATTCTGTCC-3' and 5'-CCAGTATAATGGCTACATTTTACC-3', and annealing at 54 [degrees]C.
There is little doubt that this haplotype is present because of mating with our ancestors and Neanderthals.