hantavirus pulmonary syndrome


Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia, Wikipedia.
Related to hantavirus pulmonary syndrome: leptospirosis

hantavirus pulmonary syndrome

a febrile disease caused by several species of Hantavirus (Andes, Bayou, Black Creek Canal, New York, and Sin Nombre viruses) in North and South America and characterized by thrombocytopenia, leukocytosis, and capillary leakage in the lungs, with death due to shock and cardiac complications.

hantavirus pulmonary syndrome

a sometimes fatal febrile illness caused by a virus of the genus Hantavirus, characterized by variable respiratory symptoms followed by acute respiratory distress, sometimes progressing to respiratory failure.
An often fatal respiratory tract infection with massive acute pulmonary edema often at death caused by a hantavirus; the first cluster occurred in the Four Corners region of Southwestern US
Epidemiology Mean age 32, 61% women, 72% Native American
Case definition Unexplained bilateral interstitial infiltrates on chest films, arterial O2 saturation < 90%
Prodrome Fever, myalgia (100%), cough or shortness of breath (75%), GI symptoms, headache, tachycardia, tachypnea, hypotension
Lab Leukocytosis—± 26 x 109/L—often with myeloid precursors, increased haematocrit, thrombocytopaenia of ±64 x 109/L, increased PT, increased aPTT, increased LD, decreased serum protein, proteinuria
Prevention Vaccine is being developed

hantavirus pulmonary syndrome

An often fatal RTI caused by a hantavirus; the first cluster occurred in the Four Corners region of Southwestern US Epidemiology Mean age 32, 61% ♀, 72% Native American Case definition Unexplained bilateral interstitial infiltrates on chest film, arterial O2 saturation < 90% Prodrome Fever, myalgia-100%, cough or SOB-76%, GI Sx, headache, tachycardia, tachypnea, hypotension Lab Leukocytosis–± 26 x 109/L, often with myeloid precursors, ↑ Hct, thrombocytopenia of ±64 x 109/L, ↑ PT, ↑ aPTT, ↑ LD, ↓ serum protein, proteinuria Diagnosis Immunohistochemistry, Western blot, ELISA, IgM capture ELISA; massive acute pulmonary edema is common at death

Han·ta·vi·rus pul·mo·na·ry syn·drome

(hahn'tă-vī'rŭs pul'mŏ-nar-ē sin'drōm)
A febrile disease caused by several species of Hantavirus (Andes, Bayou, Black Creek Canal, New York, and Sin Nombre viruses) in North and South America and characterized by thrombocytopenia, leukocytosis, and capillary leakage in the lungs, with death due to shock and cardiac complications.

hantavirus pulmonary syndrome

Acute respiratory illness featuring a brief period of fever, muscle pains, headache, nausea and cough followed by severe shock and pulmonary oedema simulating the acute adult RESPIRATORY DISTRESS SYNDROME (ARDS). The mortality without specific treatment is 50–75 per cent but the drug ribavirin is effective. The disease is caused by a strain of hanta virus and was originally though to be acquired only from rodents. Human case-to-case infection has now been demonstrated.
References in periodicals archive ?
A Newly Recognized Virus Associated With a Fatal Case of Hantavirus Pulmonary Syndrome in Louisiana.
Hantavirus pulmonary syndrome tends to be of shorter duration and shows disproportionately more pulmonary edema than AIP.
Hantavirus pulmonary syndrome (Rio Mamore virus) in the Peruvian Amazon region [in Spanish].
To further our knowledge of the epidemiology of the North American Tacaribe serocomplex viruses, we tested serum samples from hospitalized persons in a study of thrombocytopenic febrile illnesses that mimicked hantavirus pulmonary syndrome for IgG against arenaviruses.
Beginning around the same time, dozens of other infectious diseases--including Lyme disease, hantavirus pulmonary syndrome, West Nile virus, and Ebola hemorrhagic fever--were either newly recognized, spread to new locations, or became increasingly deadly.
It covers both vector- and zoonotic-borne diseases such as Lyme disease, ehrlichiosis, West Nile, hantavirus pulmonary syndrome, dengue, and Ebola.
Hantavirus pulmonary syndrome (HPS) is an acute viral disease, characterized by a nonspecific febrile illness followed by severe noncardiogenic pulmonary edema and cardiogenic shock.
The cast of new diseases includes HIV/AIDS, Lyme disease, Legionella infection, Ebola, Nipah virus, hantavirus pulmonary syndrome, toxic Eschericbia coli infection, a new strain of cholera, and infection by a host of antibiotic-resistant organisms [Centers for Disease Control and Prevention (CDC) 1994; Institute of Medicine 1992].
Lyme disease, caused by the bite of an infected tick, and hantavirus pulmonary syndrome, transmitted by infected rodents through urine, fecal droppings and saliva, are among other pest-borne illnesses.
On the American continents, hantaviruses can evoke a severe acute disease known as hantavirus pulmonary syndrome (HPS), which carries typical case-fatality rates of 35%-40%, depending on the particular virus (1).
Emerging diseases such as Rift Valley fever, hantavirus pulmonary syndrome, Nipah virus encephalitis, severe acute respiratory syndrome (SARS), HIV, and West Nile virus infection have become notorious.