halothane hepatitis

hal·o·thane hep·a·ti·tis

[MIM*234350]
hepatocellular damage said to result from the administration of halothane anesthesia.

halothane hepatitis

A potentially fatal hepatitis evoked by halothane, a carbon tetrachloride-related halocarbon used as a maintenance anesthetic–thiopental is often used for induction
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References in periodicals archive ?
As would be expected with idiosyncratic injury, halothane hepatitis is non-dose-related and exceedingly rare [28]; however, it exhibits characteristics of both idiosyncratic and intrinsic liver injury [29].
Metabolic basis for a drug hypersensitivity: antibodies in sera from patients with halothane hepatitis recognize liver neoantigens that contain the trifluoracetyl group derived from halothane.
Identification of the dihydrolipoamide acetyltransferase subunit of the human pyruvate dehydrogenase complex as an autoantigen in halothane hepatitis.