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haloperidol/hal·o·peri·dol/ (hal″o-per´ĭ-dol) an antipsychotic agent of the butyrophenone group with antiemetic, hypotensive, and hypothermic actions; used especially in the management of psychoses and to control vocal utterances and tics of Gilles de la Tourette's syndrome; used also as the decanoate ester in maintenance therapy for psychotic disorders.
haloperidol(hăl′ō-pĕr′ĭ-dôl′, -dŏl′, -dōl′)
An antipsychotic drug, C21H23ClFNO2, often administered in its decanoate form, used in the treatment of schizophrenia and in the management of Tourette syndrome.
a butyrophenone antipsychotic.
indications It is prescribed in the treatment of schizophrenia, in the control of tics and verbal utterance of Tourette's syndrome, in the treatment of severe behavioral problems in children, and as a sleep aid.
contraindications Parkinson's disease, concurrent administration of central nervous system depressants, liver or renal dysfunction, severe hypotension, or known hypersensitivity to this drug prohibits its use.
adverse effects There is a wide range of adverse effects. Among the more serious adverse effects are hypotension and hypersensitivity reactions. It also has comparatively high risk for a variety of extrapyramidal effects, including pseudoparkinson signs and symptoms, tardive dyskinesia, dystonia, and akathisia.
haloperidolHaldol® Psychiatry A dopamine-blocking antipsychotic for treatment-refractory schizophrenia; it ↓ hallucinations, delusions, thought disturbances, ameliorates withdrawal and apathy, used to control Sx, and to prevent relapse; it may be used for Tourette syndrome Adverse effects Sedation, weight gain, extrapyramidal signs–which may be may be immediate–eg, parkinsonism, akathisia and acute dystonia, or late with long-term therapy–eg, tardive dyskinesia, 'rabbit' syndrome, orthostatic hypotension, cardiovascular, GI effects, potentially fatal neuroleptic malignant syndrome. See Neuroleptic malignant syndrome, Positive & Negative Symptom Scale, 'Rabbit syndrome, ' Schizophrenia. Cf Clozapine.
haloperidolA butyrophenone drug used in the treatment of psychiatric disorders. It is similar in its effects to the PHENOTHIAZINE derivative drugs. The drug is on the WHO official list. Brand names are Dozic, Haldol, Haloperidol and Serenace.
haloperidolcentral nervous system-acting drug used to minimize unwanted movement, e.g. tremor of drug-induced parkinsonism; and tic-like movement characteristic of choreas
a dopamine antagonist in the brain, used as a neuroleptoanalgesic agent.