Scientists have known that this compound, called halofuginone
(a derivative of the febrifugine), can suppress parts of the immune system-but nobody knew exactly how.
Now Tracy Keller and colleagues at the Harvard School of Dental Medicine in Boston have found that halofuginone
- a chemical based on the roots' active ingredient - blocks immune reactions that can cause disease.
is derived from an alkaloid isolated from Dichroa febrifuga plant .
11 substances are concerned: Lasalocid sodium, Narasin, Salinomycin sodium, Monensin sodium, Semduramicin, Maduramicin, Robenidine, Decoquinate, Halofuginone
, Nicarbazin, and Diclazuril.
Scientists hope the compound, called halofuginone
, can be used to tackle conditions such as rheumatoid arthritis, multiple sclerosis, Type 1 diabetes, inflammatory bowel disease and psoriasis.
, a collagen type I inhibitor improve liver regeneration in cirrhotic rats.
Waban, MA; 617-244-6016), announced the receipt of United States Patent 6,028,075, for the use of their lead compound, Halofuginone
and derivatives, in the treatment of tumors including bladder, prostate, breast, skin, and lung.
Also in the research spotlight were a few synthetic medications such as halofuginone
Experts in more recent studies have suggested that halofuginone
, a compound derived from this extract's bioactive ingredient, could be used to treat many autoimmune disorders as well.
HT-100, a proprietary formulation of halofuginone
, is an orally available small molecule drug candidate being developed to reduce fibrosis and promote healthy muscle fiber regeneration in DMD patients.
HT-100, Halo's proprietary formulation of halofuginone
, is an orally available small molecule drug candidate intended to reduce fibrosis and promote healthy muscle fiber regeneration.
HT-100, also known as halofuginone
, is an orally available small molecule drug candidate that is being developed to reduce fibrosis and promote healthy muscle fiber regeneration.