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halofantrine

   Also found in: Wikipedia 0.01 sec.
halofantrine /hal·o·fan·trine/ (-fan´trēn) an antimalarial used as the hydrochloride salt in the treatment of acute malaria due to Plasmodium falciparum and P. vivax.
halofantrine,
an antimalarial.
indication It is used to treat mild to moderate malaria.
contraindication Known hypersensitivity to halofantrine prohibits its use.
adverse effects Common side effects include nausea, vomiting, anorexia, diarrhea, and arrhythmias.

halofantrine [-fan´trēn]
an antimalarial agent used as the hydrochloride salt in treatment of acute malaria due to Plasmodium falciparum or P. vivax.


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Affected drugs are Chloroquine, sulphadoxine-pyrimethamine, halofantrine, co-trimoxazole, Amoxycillin, Ampicillin, Ciprofloxacin, erythromycin, Gentamicin, Metronidazole, Tetracycline, Cefalexin, Lincomycin, Oxtetracyclin.
12) Halofantrine treatment is not advisable given the associated cardiotoxicity, variable bioavailability and drug interactions in patients who have taken mefloquine prophylaxis.
 
 
 
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