hairy cell


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hairy cell

(hâr′ē)
n.
A white blood cell having multiple surface projections and characteristically present in hairy cell leukemia.
Haematology A round or ovoid, 12–20-µm peripheral blood cell characterised by filamentous projections that are fine/hairy by phase contrast and electron microscopy, but thick or smudged and irregular by light microscopy; hairy cells are monotonously uniform in appearance; the nucleus is ovoid and may be indented, and usually central, but may be eccentric with 1+ nucleoli; the chromatin is fine or slightly coarse; the moderate amount of cytoplasm stains pale blue; N:C ratio is 4:1 to 2:1

hair·y cell

(hār'ē sel)
Medium-sized leukocytes that have features of reticuloendothelial cells and multiple cytoplasmic projections (hairs) on the cell surface, but may be a variety of B lymphocyte; found in hairy cell leukemia.
References in periodicals archive ?
Hairy cell lymphoma: a unique presentation of hairy cell leukaemia.
Hairy cell leukemia could now be included in this group of diseases.
Hairy cell leukemia: a clinical review based on 725 cases of the Italian Cooperative Group (ICGHCL).
When we normalized with CD19 mRNA, most of the B-NHL-other samples separated away from the MCL samples, except for several patients with hairy cell leukemia, follicular lymphoma, and diffuse large B-cell lymphoma.
Concentrations of organochlorines related to titers to Epstein-Barr virus early antigen IgG as risk factors for hairy cell leukemia.
However, when hairy cell leukemia patients become resistant to these drugs--as had all 16 people in this study--they face a dire prognosis.
Detection of minimal residual disease by immunostaining of bone marrow biopsics after 2-chlorodeoxyadenosine for hairy cell leukemia.
Hairy cell is an extremely rare strain of the lymphocytic type, so rare that many physicians never encounter the disease.
A snapshot of the global therapeutic scenario for Hairy Cell Leukemia.
Therapy for neutropenia in hairy cell leukemia with recombinant human granulocyte colony-stimulating factor.
Around 21,500 people get leukaemia in the UK every year but fewer than 100 get the hairy cell leukaemia which attacked his body.