Type 2 diabetes alters the functional status of outer hair cells
in the cochlea.
Morphologically, intact hair cells
maintained their kinociliary bundles, whereas damaged hair cells
had hair cell
bundles that were splayed, frayed, or missing.
Whereas previous research indicated that hair cells
are not replaced, this latest study found that replacement does indeed occur, but at very low levels.
The cause is mostly damage to the inner hair cells
specialized sensory cells in the inner ear that transmit information about sounds through the nervous system to the brain.
Rescue of hearing, auditory hair cells
, and neurons by CEP-1347/KT7515, an inhibitor of c-Jun N-terminal kinase activation.
Thus, the full range of loudness detection may be a coding property of multiple nerve fibers attached to the same hair cell
Eight weeks after treatment, we found new auditory hair cells
in the Atohl-treated ears of the research animals," reports Dr.
The tiny hair cells
in the inner ear can become damaged from the strong vibrations or from too much "wear and tear" on them.
Interruption of the blood supply through the labyrinthine artery for longer than 15 seconds results in hair cell
and VIIIth nerve dysfunction which, if continued, is irreversible (Baloh, 1996b).
Different sounds move to the population of hair cells
in different ways, thus allowing the brain to distinguish among various sounds, for example, different vowel and consonant sounds.
As a result of these acquisitions, the company's business became the development of hair cell
In an animal with normal hearing, tiny muscles in the middle ear contract to reduce the transmission of extremely loud sounds to the inner ear that would reduce hair cell