haemosiderinuria

haemosiderinuria

The presence of HAEMOSIDERIN in the urine. This occurs in cases of excessive breakdown of red blood cells with release of haemoglobin. Most of this is taken up by a serum protein haptoglobin, but if all the haptoglobin is consumed free haemoglobin damages the kidney tubules and haemosiderin appears in the urine.
References in periodicals archive ?
Laboratory findings Suggest haemolysis * Full blood count: reticulocytosis with or without low Hb; mild macrocytosis * Blood smear: polychromasia and basophilic stippling * Liver function test: increased unconjugated bilirubin and LDH or AST To confirm haemolysis * Decreased haptoglobin Features suggestive of intravascular haemolysis * Haemoglobinaemia * Haemoglobinuria * Haemosiderinuria Hb = haemoglobin; LDH = lactate dehydrogenase; AST = aspartate aminotransferase Table II.