haemophagocytic syndrome

haemophagocytic syndrome

A disease in which the large scavenging cells, the MACROPHAGES or histiocytes, attack blood forming tissues in the bone marrow, causing severe anaemia and bleeding tendency. Some cases are due to infection with herpes viruses, such as the cytomegalovirus and the EPSTEIN-BARR VIRUS, and these tend to be very serious.
References in periodicals archive ?
Infections associated with haemophagocytic syndrome.
Clinical features of haemophagocytic syndrome in patients with systemic autoimmune diseases: analysis of 30 cases.
Viral infections associated with haemophagocytic syndrome.
Specific clinical parameters have been identified by Oksenhendler [6] to increase the rate of diagnosing Castleman's disease in HIV-positive individuals, including fever, diffuse lymphadenopathy, splenomegaly, severe cytopenia, high serum C-reactive protein levels, elevated HHV-8 DNA levels in peripheral blood mononuclear cells, extreme plasmacytosis in lymph nodes or bone marrow, nasal obstruction, respiratory symptoms, Kaposi's sarcoma lesions, a previous similar episode with spontaneous resolution, positive Coombs' test and haemophagocytic syndrome.
Haemophagocytic syndrome in Plasmodium falciparum malaria.
A French retrospective study of 58 HIV-positive patients showed that reactive haemophagocytic syndrome was diagnosed in patients with a median [CD4.
Haemophagocytic syndrome is a reactive disorder of the mononuclear phagocytic system, characterised by histiocytic proliferation with marked Haemophagocytosis (3).
Metastatic involvement with tumors,10 granulomatous diseases,11 storage disorder,12 haemophagocytic syndrome,13 and Leishmaniasis.
Influenza A virus-associated encephalopathy with haemophagocytic syndrome.
Haemophagocytic syndrome may also be suggested by bone marrow examination findings.
15 Lysosomal storage disorders and haemophagocytic syndromes have been reported to be often diagnosed mainly by bone marrow examination16 in this study Gaucher\'s disease was found in five cases and haemophagocytic syndrome in three cases.
Haemotological malignancy, haemophagocytic syndrome, malaria and leishmaniasis were ruled out from the blood smear and bone marrow examination.