The sample consisted of children aged 1 month to 17 years, presenting with clinical symptoms and signs suggestive of haemolytic anaemia
and those with peripheral blood smear suggestive of haemolysis.
10] Haemolytic anaemia
, thrombocytopenia, fever, neurological features and renal dysfunction may all be erroneously attributed to a CTD flare, especially in the case of SLE where a lupus flare may present in this exact way.
When haemolytic anaemia
remains severe despite glucocorticoid therapy, or if very large doses are necessary to maintain a reasonable haemoglobin (HB) level, intravenous immunoglobulin (IVIG) may be tried.
Concurrent immune-mediated haemolytic anaemia
and severe thrombocytopenia in 21 dogs.
Both patients subsequently developed renal failure with associated anaemia, thrombocytopenia and red cell fragmentation consistent with microangiopathic haemolytic anaemia
Other rare causes of spherocytosis include thermal injury, clostridial septicaemia with exotoxaemia, and Wilson's disease, which may present with transient haemolytic anaemia
Red blood cell transfusion in warm-type autoimmune haemolytic anaemia
IMMUNE mediated haemolytic anaemia
(IMHA) is where the body's immune system attacks and destroys its own red blood cells (that carry oxygen in the blood) or platelets (that help with clotting).
Indications for transfusion include symptomatic anaemia, haemolytic anaemia
, haematological malignancy, acute sickle cell crisis and acute blood loss of more than 30 percent of blood volume, sepsis, etc.
The United States Food and Drug Administration has granted orphan drug designation to United States-based Agios Pharmaceuticals' AG-348, intended to treat pyruvate kinase deficiency, a rare form of haemolytic anaemia
, it was reported yesterday.
History of neonatal jaundice, microangiopathic haemolytic anaemia
and thrombocytopenia favoured congenital TTP.
Excessive apoptosis of bone marrow erythroblasts in a patient with autoimmune haemolytic anaemia