haemolysis


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haemolysis

See hemolysis.

he·mol·y·sis

(hē-mol'i-sis)
Alteration, dissolution, or destruction of red blood cells in such a manner that hemoglobin is liberated into the medium in which the cells are suspended.
Synonym(s): erythrocytolysis, erythrolysis, hematolysis, haemolysis.
[hemo- + G. lysis, destruction]

haemolysis

Destruction of red blood cells by rupture of the cell envelope and release of the contained HAEMOGLOBIN. This occurs when red cells are placed in fluids more dilute than serum or as a result of an immune-mediated process. It may result from excessive trauma to red cells as in passage through artificial heart valves. Haemolysis also occurs when there is an inherent weakness in the cell membrane as in HEREDITARY SPHEROCYTOSIS. It also occurs in many other conditions including GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY, various HAEMOGLOBINOPATHIES, THALASSAEMIA, rhesus factor incompatibility (ERYTHROBLASTOSIS FETALIS) and vitamin K overdosage.

haemolysis

the disintegration of red blood cells, with the release of HAEMOGLOBIN. The process can occur
  1. when the cells take in excess water by OSMOSIS,
  2. when there is an antigen-antibody reaction involving the cells, as in RHESUS HAEMOLYTIC ANAEMIA,
  3. as a result of an abnormality such as FAVISM. Addition of glacial acetic acid to a blood sample causes haemolysis of the red blood cells, thus making it easier to observe and count the white blood cells.

he·mol·y·sis

(hē-mol'i-sis)
Alteration, dissolution, or destruction of red blood cells in such a manner that hemoglobin is liberated into the medium in which the cells are suspended.
Synonym(s): haemolysis.
[hemo- + G. lysis, destruction]
References in periodicals archive ?
Influence of haemolysis on troponin testing: studies on Beckman Coulter UniCel Dxl 800 Accu-Tnl and overview of the literature.
22,23] Increased uric acid might be a consequence of increased cell turnover because of exaggerated haemolysis or an attempt to scavenge increased free oxygen radicals as uric acid also behaves as a powerful antioxidant and scavenger of singlet oxygen radicals.
Thus subnormal concentration of ATP predisposes RBCs to altered structures and function, a loss of normal deformability, increase in fragility and haemolysis resulting in haemoglobinemia and haemoglobinuria (Bhikane et al.
Surveying of role Hemiscorpius lepturus scorpion venom in red cell haemolysis.
The release of haemoglobin in the supernatant following haemolysis was measured using a spectrophotometer (LKB Ultrospec II, LKB Biochrom Ltd London, UK) at 540 nm with distilled water as a blank.
We used haemolysis of erythrocytes as a model for the physical membrane effects and cytotoxicity against the two cancer cell lines HeLa and Cos7 to monitor the effects on living cells.
The patient's symptoms of severe hypertension, haemolysis, thrombocytopaenia and renal failure were consistent with malignant hypertension, and treating the hypertension (7) gradually resolved the thrombocytopaenia, haemolysis and renal failure (8).
All the isolates that were positive for hbl genes in PCR exhibited haemolysis in SBA.
Common causes of anaemia in lupus are autoimmune-mediated red cell haemolysis, bone marrow suppression and drug-induced gastrointestinal blood loss.
In the presence of a large number of spherocytes in the peripheral blood film, a major alternative differential diagnosis was autoimmune haemolysis (which can mimic HS).
The preliminary blood compatibility studies showed that surface modification using DAPEG reduces platelet activation and haemolysis in contrast to the surfactant stabilized GNPs significantly enhances the haemolysis by comparing with positive control.