Each patient underwent clinical evaluation and investigations for screening of DHF diagnosis based on Dengue Expert Advisory Group (DEAG) criteria according to which DHF is characterised by plasma leakage as shown by haemoconcentration
(an increase in Hct >20% above average for age or decrease in Hct >20% of baseline following fluid replacement therapy, pleural effusion, ascites, or hypoproteinaemia.
The systemic capillary leak syndrome (SCLS) is characterized by spontaneous recurrent episodes of hypotension, haemoconcentration
, generalized oedema, and in most cases, the presence of a paraprotein.
14] have suggested that protein C may leave the plasma during the period of haemoconcentration
that occurs in acutely cooled subjects.
The factors significantly associated with poor prognosis group (DHF/DSS) were anorexia, altered mentation, conjunctival injections, anaemia with Hb < 10 mg%, haemoconcentration
with haematocrit > 40, thrombocytopenia and deranged liver enzymes SGOT.
positive tourniquet test; patechiae, ecchymoses, or purpura; epistaxis or bleeding from mucosa, gastrointestinal tract, injection sites or others), thrombocytopenia (moderate to marked drop in platelets), and haemoconcentration
(raised Packed Cell Volume).
If there is little or no fluid coming in from the tissues, the patient may be at risk of excessive haemoconcentration
, ventilatory acclimatization) or even years or generations (e.
Application of torniquette was avoided or minimized to 30 seconds to avoid the effect of haemoconcentration
These changes could not be explained by haemoconcentration
but were related to a suppressed renal function with diminished renal blood flow, decreased glomerular filtration rate and increased hyperaldosteronemia-related renal sodium-re-uptake as well as to proteolysis during prolonged exercise.
and accumulation of white cells in the feet during venous stasis.
Dengue haemorrhagic fever is characterised by high fever, haemorrhagic phenomenon, hepatomegaly and shock, moderate to marked thrombocytopenia with concurrent haemoconcentration