haemochromatosis


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

haemochromatosis

he·mo·chro·ma·to·sis

(hē'mō-krō-mă-tō'sis)
A disorder of iron metabolism characterized by excessive absorption of ingested iron, saturation of iron-binding protein, and deposition of hemosiderin in tissue, particularly in the liver, pancreas, and skin; cirrhosis, diabetes mellitus (bronze diabetes), bronze pigmentation of the skin, and, eventually heart failure may occur; also can result from administration of large amounts of iron orally, by injection, or in forms of blood transfusion therapy.
Synonym(s): haemochromatosis.
[hemo- + G. chrōma, color, + -osis, condition]

haemochromatosis

A rare genetic disease featuring abnormal absorption and retention of iron. Total body iron may rise from the normal 4 or 5 g to as much as 60 g and the stored iron may cause CIRRHOSIS of the liver, DIABETES, IMPOTENCE, HEART FAILURE and bronzing of the skin. Treatment is by regular weekly bleeding until the levels of serum iron reach normal. The drug desferrioxamine is also useful.

he·mo·chro·ma·to·sis

(hē'mō-krō-mă-tō'sis) [MIM*235200]
Disorder of iron metabolism characterized by excessive absorption of ingested iron, saturation of iron-binding protein, and deposition of hemosiderin in tissue, particularly in the liver, pancreas, and skin; cirrhosis, diabetes (bronze diabetes), bronze pigmentation of the skin, and, eventually heart failure may occur; can also result from administration of large amounts of iron orally, by injection, or in forms of blood transfusion therapy.
Synonym(s): haemochromatosis.
[hemo- + G. chrōma, color, + -osis, condition]
References in periodicals archive ?
HAC Ahead of National Haemochromatosis Awareness Day today, Conor Kenny, a business strategist from Ballinteer in Dublin, spoke about his initial fears when he was diagnosed in December.
Ejaculatory failure and hypogonadotrophic hypogonadism caused by haemochromatosis.
As a result it is important for all medical practitioners to be aware of haemochromatosis and its risk factors and to start treatment as early as possible.
Search terms included hemochromatosis, haemochromatosis, hereditary hemochromatosis, diet, iron, absorption, ironoverload, tea, polyphenol, tannin, gallic acid, gallate, ferritin, wine and coffee in various combinations.
Haemochromatosis is a condition that allows the sufferer to absorb an excess of iron from food, which is then stored around various internal organs, especially the heart and liver, with potentially fatal consequences.
He had, in fact, an inherited blood condition called haemochromatosis.
The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22.
It is predominantly found in men 50-60 years of age, and is most commonly due to cirrhosis secondary to alcoholism, viral Hepatitis B or C, haemochromatosis, or autoimmune diseases.
I had Haemochromatosis, an iron overload which stops the organ working.
The origin and spread of the HFE-C282Y haemochromatosis mutation.
Hethought I might be suffering from haemochromatosis, which is an excess of iron in the blood.
Urinary or serum hepcidin concentrations are widely altered in anaemia of chronic infection, iron overload, iron deficiency and haemochromatosis (52).