haemolysis

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haemolysis

See hemolysis.

he·mol·y·sis

(hē-mol'i-sis)
Alteration, dissolution, or destruction of red blood cells in such a manner that hemoglobin is liberated into the medium in which the cells are suspended.
Synonym(s): erythrocytolysis, erythrolysis, hematolysis, haemolysis.
[hemo- + G. lysis, destruction]

haemolysis

Destruction of red blood cells by rupture of the cell envelope and release of the contained HAEMOGLOBIN. This occurs when red cells are placed in fluids more dilute than serum or as a result of an immune-mediated process. It may result from excessive trauma to red cells as in passage through artificial heart valves. Haemolysis also occurs when there is an inherent weakness in the cell membrane as in HEREDITARY SPHEROCYTOSIS. It also occurs in many other conditions including GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY, various HAEMOGLOBINOPATHIES, THALASSAEMIA, rhesus factor incompatibility (ERYTHROBLASTOSIS FETALIS) and vitamin K overdosage.

haemolysis

the disintegration of red blood cells, with the release of HAEMOGLOBIN. The process can occur
  1. when the cells take in excess water by OSMOSIS,
  2. when there is an antigen-antibody reaction involving the cells, as in RHESUS HAEMOLYTIC ANAEMIA,
  3. as a result of an abnormality such as FAVISM. Addition of glacial acetic acid to a blood sample causes haemolysis of the red blood cells, thus making it easier to observe and count the white blood cells.

he·mol·y·sis

(hē-mol'i-sis)
Alteration, dissolution, or destruction of red blood cells in such a manner that hemoglobin is liberated into the medium in which the cells are suspended.
Synonym(s): haemolysis.
[hemo- + G. lysis, destruction]