Haematin | definition of haematin by Medical dictionary
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haematin The iron-containing portion of HAEMOGLOBIN. A complex of PORPHYRIN, iron and hydroxide ion.
haematin an iron-containing pigment that is derived from the breakdown of HAEMOGLOBIN.
References in periodicals archive
therapy temporarily down-regulates hepatic ALAS1 activity, thereby reducing the overproduction of potentially neurotoxic metabolites by the liver.
This substance haematin
has little or no affinity for tissue elements and requires an inorganic ion to act as a "go between" (called a mordant) between the dye and the tissue.
24) In treatment of malaria, CQ binds to the haematin
(a toxic by product of hemoglobin proteolysis containing iron as a center) and prevents its incorporation in to haemozoin.
During this process a build up of haematin
occurs which is potentially toxic to the parasite (Fig.