GUSTO

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GUSTO

Cardiology A series of clinical trials that have examined a series of strategies to reduce the M&M of acute MI; the GUSTOs include: Global Utilization of Streptokinase & tPA for Occluded coronary arteries trial–GUSTO I; Global Use of Strategies to Open Occluded arteries: recombinant hirudin versus heparin as adjuncts to thrombolysis and aspirin–GUSTO II; primary coronary angioplasty with tPA–GUSTO IIb; efficacy of alteplase and reteplase–GUSTO III; platelet glycoprotein IIb/IIIa receptor inhibitor–abciximab and reteplase v. reteplase alone–GUSTO V; Strategies for Patency Enhancement in Emergency Department–GUSTO-SPEED. See Abciximab, Acute coronary syndrome, Acute myocardial infarction, Heparin, Hirudin, Reteplase, Streptokinase, tPA.