gumma

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gumma

 (pl. gummas, gum´mata)
1. a soft, gummy tumor occurring in tertiary syphilis.

gum·ma

, pl.

gum·ma·ta

,

gum·mas

(gŭm'ă, ă-tă, -ĕz),
An infectious granuloma that is characteristic of tertiary syphilis, but does not always develop, and that may be solitary (as large as 8-10 cm in diameter) or multiple and diffusely scattered (1 mm or less in diameter). Gummata are characterized by an irregular central portion that is firm, sometimes partially hyalinized, and consisting of coagulative necrosis in which "ghosts" of structures may be recognized; a poorly defined middle zone of epithelioid cells, with occasional multinucleated giant cells; and a peripheral zone of fibroblasts and numerous capillaries, with infiltrated lymphocytes and plasma cells. As gummas become older, an irregular scar or rounded fibrous nodule persists.
Synonym(s): syphiloma
[L. gummi, gum, fr. G. kommi]

gumma

/gum·ma/ (gum´ah) pl. gummas, gum´mata  
1. a soft, gummy tumor, such as that occurring in tertiary syphilis.
2. late benign syphilis.

gumma

(gŭm′ə)
n. pl. gummas or gummata (gŭm′ə-tə)
A small rubbery granuloma that has a necrotic center and is enclosed by an inflamed fibrous capsule. It is characteristic of an advanced stage of syphilis.

gum′ma·tous adj.

gumma

[gum′ə] pl. gummas, gummata
Etymology: AS, goma, gum
1 a granuloma, characteristic of tertiary syphilis, varying from 1 mm to 1 cm in diameter. It is usually encapsulated and contains a central necrotic mass surrounded by inflammatory and fibrotic zones of tissue. Infectious organisms of the genus Treponema may be found in a gumma. The lesion may be localized or diffuse, occurring on the trunk, legs, and face and on various internal organs, especially the liver. It can also form in the brain, leading to neurological problems. Rupture of a gumma produces a shallow ulcer that heals slowly.
2 a soft granulomatous lesion that sometimes accompanies tuberculosis.
enlarge picture
Gumma on the palate

gumma

STD Lentil-to-cherry-sized masses characteristic of tertiary syphilis, which represent a hypersensitivity response to treponemal products–the organism itself is rarely found. See Syphilis.

gum·ma

, pl. gummata (gŭm'ă, -tă)
An infectious granuloma that is characteristic of tertiary syphilis. Gummata are characterized by an irregular central portion that is firm, sometimes partially hyalinized, and consisting of coagulative necrosis in which "ghosts" of structures may be recognized; a poorly defined middle zone of epithelioid cells, with occasional multinucleated giant cells; and a peripheral zone of fibroblasts and numerous capillaries, with infiltrated lymphocytes and plasma cells.
Synonym(s): syphiloma.
[L. gummi, gum, fr. G. kommi]

gumma

One of the principle features of late (tertiary) SYPHILIS. The gumma is a localized mass of GRANULATION TISSUE, with a necrotic centre of a gum-like consistency. It occurs as a result of toxic destruction of tissue and can occur anywhere in the body, including the intestines, the liver and the brain.

Gumma

A symptom that is sometimes seen in tertiary syphilis, characterized by a rubbery swelling or tumor that heals slowly and leaves a scar.
Mentioned in: Syphilis

gum·ma

, pl. gummata (gŭm'ă, -tă)
An infectious granuloma that is characteristic of tertiary syphilis. Gummata are characterized by an irregular central portion that is firm, sometimes partially hyalinized, and consisting of coagulative necrosis.
Synonym(s): syphiloma.
[L. gummi, gum, fr. G. kommi]

gumma (gum´ə),

n a granulomatous, gummy lesion of tertiary syphilis. The palate and tongue are sites of predilection in the oral region. A similar lesion occurring with tuberculosis is designated a tuberculous gumma.

gumma

a soft, gummy tumor.