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guanylate cyclase

   Also found in: Wikipedia 0.02 sec.
guanylate cyclase
enzyme catalyzing the synthesis of 3′5′ cyclic-GMP from GTP in photoreceptor cells of the retina in its dark state. cGMP binds to Na+-channels of the retinal cells, causing them to open.


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Lead-induced downregulation of soluble guanylate cyclase in isolated rat aortic segments mediated by reactive oxygen species and cyclooxygenase-2.
coli CNF Deamidase LT ADP- ribosyltransferase ST(d) Stimulates guanylate cyclase CLDT(d) G2 block EAST ST-like?
Once produced, NO diffuses to the vascular smooth muscle cells where it activates the enzyme guanylate cyclase, leading to increased cGMP levels and to vascular smooth muscle relaxation.
 
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