guanosine triphosphate


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Related to guanosine triphosphate: adenosine triphosphate, GTP

guanosine

 [gwah´no-sēn]
a nucleoside, guanine riboside, one of the major constituents of RNA.
cyclic guanosine monophosphate a cyclic nucleotide, guanosine 3′,5′-cyclic monophosphate, an intracellular “second messenger” similar in action to cyclic adenosine monophosphate; the two cyclic nucleotides activate different protein kinases and usually produce opposite effects on cell function. Abbreviated 3′,5′-GMP, cGMP, and cyclic GMP.
guanosine monophosphate (GMP) a nucleotide important in metabolism and RNA synthesis.
guanosine triphosphate (GTP) a nucleotide required for RNA synthesis and involved in energy metabolism.

guanosine triphosphate

n.
GTP.

guanosine triphosphate (GTP)

a high-energy nucleotide, similar to adenosine triphosphate, that functions in various metabolic reactions, such as the activation of fatty acids and the formation of peptide bonds in protein synthesis.

guanosine

a nucleoside, guanine riboside, one of the major constituents of nucleic acids.

cyclic guanosine monophosphate (cyclic GMP, cGMP)
a cyclic 3′,5′-phosphate that acts as an intercellular second messenger mediating the activity of hormones and other substances; essential in vision where cGMP concentrations increase in the dark.
guanosine monophosphate
a nucleotide important in metabolism and nucleic acid synthesis; called also GMP.
guanosine pentophosphate
involved with guanosinetetraphosphate in the so called stringent response of bacteria in which, because the cell does not have a sufficient pool of amino acids to maintain protein synthesis, tRNA and rRNA synthesis is reduced by about 20-fold, which suspends many of the cells' activities until conditions improve.
guanosine tetraphosphate
see guanosine pentophosphate (above).
guanosine triphosphate
an energy-rich compound involved in several metabolic reactions; called also GTP.
References in periodicals archive ?
RPMI-8226R was subjected to microarray gene expression profiling, and guanosine triphosphate (GTP) level was determined with the objective of comparing these biomarkers to the same markers in patient samples from the Phase I clinical trial.
AVN944 is an oral, small molecule inhibitor of the enzyme inosine monophosphate dehydrogenase (IMPDH), an enzyme that is essential for the de novo synthesis of the nucleotide guanosine triphosphate (GTP).
AVN944 is an inhibitor of the enzyme inosine monophosphate dehydrogenase (IMPDH), an enzyme that is essential for the de novo synthesis of the nucleotide guanosine triphosphate (GTP).
IMPDH inhibition leads to a reduction in intracellular guanosine triphosphate (GTP), a molecule required for DNA and RNA synthesis.