GNB3

(redirected from guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 3)

GNB3

A gene on chromosome 12p13 that encodes a beta subunit of a heterotrimeric guanine nucleotide-binding protein (G protein), which regulates signal transduction between receptors and effectors.

Molecular pathology
A single-nucleotide polymorphism in GNB3 is associated with essential hypertension and obesity.
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