somatostatin

(redirected from growth hormone-inhibiting hormone)
Also found in: Dictionary, Acronyms, Encyclopedia.
Related to growth hormone-inhibiting hormone: thyroid hormone, Corticotropin releasing hormone, Thyrotropin releasing hormone, Prolactin Inhibiting Hormone

somatostatin

 (SRIF, SS) [so″mah-to-stat´in]
a cyclic tetradecapeptide hormone and neurotransmitter that inhibits the release of peptide hormones in many tissues. It is released by the hypothalamus to inhibit the release of growth hormone (GH, somatotropin) and thyroid stimulating hormone (TSH) from the anterior pituitary; it is also released by the delta cells of the islets of Langerhans in the pancreas to inhibit the release of glucagon and insulin and by the similar D cells in the gastrointestinal tract.

so·ma·to·stat·in

(sō'mă-tō-stat'in), [MIM*182450]
A tetradecapeptide capable of inhibiting the release of somatotropin by the anterior lobe of the pituitary gland; somatostatin has a short half-life; it also inhibits the release of insulin, glucagon, and gastrin. Used in the treatment of acromegaly, gigantism, and pancreatic tumors.
[somatotropin + G. stasis, a standing still, + -in]

somatostatin

/so·ma·to·stat·in/ (SS) (-stat´in) a polypeptide elaborated primarily by the median eminence of the hypothalamus and by the delta cells of the islets of Langerhans; it inhibits release of thyrotropin, somatotropin, and corticotropin by the adenohypophysis, of insulin and glucagon by the pancreas, of gastrin by the gastric mucosa, of secretin by the intestinal mucosa, and of renin by the kidney.

somatostatin

(sō-măt′ə-stăt′n, sō′mə-tə-)
n.
A polypeptide hormone produced chiefly by the hypothalamus that inhibits the secretion of various other hormones, such as somatotropin, glucagon, insulin, thyrotropin, and gastrin.

somatostatin

[sō′matōstat′in]
a hormone produced in the hypothalamus that inhibits the release of somatotropin (growth hormone) from the anterior pituitary gland. It also is produced in other parts of the body and inhibits the release of certain other hormones, including thyrotropin, adrenocorticotropic hormone, glucagon, insulin, and cholecystokinin, and of some enzymes, including pepsin, renin, secretin, and gastrin. Also called growth hormone release inhibiting hormone.

so·ma·to·stat·in

(sō'mă-tō-stat'in)
A tetradecapeptide capable of inhibiting release of somatotropin, insulin, and gastrin.
Compare: bioregulator
Synonym(s): growth hormone-inhibiting hormone, somatotropin release-inhibiting hormone.
[somato- + G. stasis, a standing still, + -in]

somatostatin

a hormone of the hypothalamus that inhibits the release of growth hormone from the pituitary gland.

somatostatin

hormone secreted at several sites, with widespread inhibitory effects on other secretions: from the hypothalamus, as growth hormone-inhibiting hormone (GH-IH) acting in the anterior pituitary; in the pancreas, inhibits other pancreatic secretions; from the intestinal wall, inhibits many hormonal and enzyme secretions in the gut.

so·ma·to·stat·in

(sō'mă-tō-stat'in) [MIM*182450]
Tetradecapeptide capable of inhibiting release of somatotropin by anterior lobe of pituitary gland.
[somatotropin + G. stasis, a standing still, + -in]

somatostatin

a cyclic tetradecapeptide hormone and neurotransmitter that inhibits the release of peptide hormones in many tissues. It is released by the hypothalamus to inhibit the release of growth hormone (GH, somatotropin) and thyroid-stimulating hormone (TSH) from the anterior pituitary; it is also released by the delta cells of the islets of Langerhans in the pancreas to inhibit the release of glucagon and insulin and by the similar D cells in the gastrointestinal tract.
Full browser ?