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growth hormone insensitivity syndrome

   Also found in: Acronyms 0.01 sec.
growth hormone insensitivity syndrome
Laron dwarfism, pituitary dwarfism II An AR condition characterized by severe growth retardation, delayed bone age, occasionally blue sclerae, and physical manifestations of GH deficiency, due to a defect in the GH receptor


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Tercica's suit in the UK alleges that by making, using, and selling the SomatoKine product in the United Kingdom for the treatment of Growth Hormone Insensitivity Syndrome (GHIS), Avecia and Insmed infringe a European (UK) patent under which Tercica holds an exclusive license from Genentech.
The product also has received European orphan drug designation for growth hormone insensitivity syndrome (GHIS), which the FDA has determined to be equivalent to Primary IGFD and GH gene deletion.
Previously Insmed referred to its primary indication as Growth Hormone Insensitivity Syndrome (GHIS).
 
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