growth factor receptor


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growth factor receptor

a plasma membrane-spanning protein that binds with a specific growth factor on the external surface of a cell and transduces a signal that triggers cell division.
References in periodicals archive ?
The results indicate that the interactions between estrogen, progesterone and epidermal growth factor receptor pathways may be considered relevant targets for the treatment of hormone-dependent breast cancers," she said.
A combined approach of inhibiting both the hormones and the epidermal growth factor receptor may be beneficial for some women in treating hormone-dependent breast cancer.
Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin.
Epidermal growth factor receptor immunohistochemical reactivity in patients with American Joint Committee on Cancer Stage IV colon adenocarcinoma: implications for a standardized scoring system.
The prognostic significance of proliferating cell nuclear antigen, epidermal growth factor receptor, and mdr gene expression in colorectal cancer.
Growth inhibition of human tumor cells in athymic mice by anti-epidermal growth factor receptor monoclonal antibodies.
Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice.
Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in a human tumor xenograft model.
Panitumumab is an investigational fully human monoclonal antibody that targets the epidermal growth factor receptor (EGFr), a protein that plays an important role in cancer cell signaling.
ERBITUX is an IgG1 monoclonal antibody (IgG1 MAb) designed to inhibit the function of a molecular structure expressed on the surface of normal and tumor cells called the epidermal growth factor receptor (EGFR, HER1, c-ErbB-1).
AMG 706 is believed to inhibit the activity of all three receptors in the Vascular Endothelial Growth Factor receptor (VEGFr) family that are the main drivers of angiogenesis.
The second antibody, IMC-11F8, is a high affinity antibody that blocks ligand-dependent activation of the epidermal growth factor receptor (EGFR).