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growth factor receptor

   Also found in: Acronyms, Wikipedia 0.03 sec.
growth factor receptor,
a plasma membrane-spanning protein that binds with a specific growth factor on the external surface of a cell and transduces a signal that triggers cell division.


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Drugs that target the epidermal growth factor receptor, or EGFR, have been used for a number of cancers.
Purpose: Epidermal Growth Factor Receptor (EGFR) stimulates proliferation, and been shown to be overexpressed in many cancers.
In the last few years the epithelial growth factor receptor (EGFR) has emerged as one of the most important targets for drug development in oncology because it is strongly associated with malignant proliferation and adverse prognosis.
 
 
 
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