GAS2

(redirected from growth arrest-specific 2)

GAS2

A gene on chromosome 11p14.3 that encodes growth arrest-specific 2, a ubiquitously expressed caspase-3 substrate which plays a role in regulating microfilament and cell shape changes during apoptosis; it also modulates cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. It is highly expressed in the liver, lungs and kidneys.
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