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Grenz Zone

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Grenz Zone
A well-demarcated zone of separation in the upper dermis delineated by the collagen of the flattened basal epidermis from the upper dermis, the latter of which often has a dense, usually lymphocytic infiltrate. A grenz zone is seen in granuloma faciale, lepromatous leprosy, and lymphocytoma cutis and may separate a pilar tumour or leiomyoma from atrophic overlying skin

grenz zone
a zone of relatively normal collagen demarcating the boundary between normal epidermis and a dermal lesion such as a granuloma or a neoplasm.


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Biopsies showed increased Grenz zone collagen, as well as increased staining for mRNA for type I collagen.
Results showed a 50-80% increase in Grenz zone collagen (upper dermal collagen) in two of the three formulations designed to optimize growth factor penetration.
 
 
 
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