Marburg disease

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Mar·burg dis·ease

infection with an unusual rhabdovirus composed of RNA and lipid, tentatively assigned to the family of Filoviridae. Virus is "pantropic" and affects most organ systems. The disease, characterized by a prominent rash and hemorrhages in many organs, is often fatal. First seen among laboratory workers in Marburg, Germany, exposed to African green monkeys. Some interhuman spread has been observed. Attempts to isolate virus should be done only in high-security laboratories.
A rare viral haemorrhagic fever which occurs in miniclusters in Europe and Africa following direct contact with monkey tissue, blood or human serum infected with the Marburg virus.
Incubation 5-9 days; otherwise like Argentine or Bolivian hemorrhagic fever—headaches, fever, diarrhoea, myalgias, rash, pharyngitis, thrombocytopenia, leukopenia, hemorrhage, renal failure
Mortality 7 of the 31 original Marburg cohort died

Mar·burg dis·ease

(mahr'bĕrg di-zēz')
Infection caused by a virus of the order Mononegavirales and the family Filoviridae and of the genus Marburg. The virus is "pantropic" and affects most organ systems. The disease is characterized by a prominent rash and hemorrhages in many organs and is often fatal. It was first seen in Marburg, Germany in 1967, among laboratory workers exposed to African green monkeys. Some person-to-person spread has been observed. Attempts to isolate the virus should be done only in high-security laboratories.
See also: Marburg virus
Synonym(s): Marburg virus disease.

Marburg disease

A severe infectious disease that first occurred in laboratory workers in Marburg, West Germany, handling monkey tissue from Uganda. The disease subsequently occurred in Zaire. It is caused by the Marburg/Ebola virus and features fever, severe aching in the muscles, diarrhoea, sore throat, an extensive livid rash, enlarged lymph nodes, internal bleeding, pneumonia, ENCEPHALITIS and kidney failure. There is no specific treatment and the mortality can be as high as 90% in untreated cases. With good supportive care the mortality is about 25%.

Marburg,

city in Germany.
Marburg disease - characterized by a prominent rash and hemorrhages in many organs; often fatal. Synonym(s): African hemorrhagic disease; green monkey disease; Marburg virus
Marburg virus - Synonym(s): Marburg disease

Marburg disease

a severe, often fatal, viral hemorrhagic fever of humans first reported in Marburg, Germany, among laboratory workers exposed to African green monkeys. The virus is a member of the family Filoviridae.