granulomatous disease

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Related to granulomatous disease: granulomatous inflammation, granulomatous rosacea, granulomatous skin disease

chron·ic gran·u·lom·a·tous dis·ease

a congenital defect in the killing of phagocytosed bacteria by polymorphonuclear leukocytes, which cannot increase their oxygen metabolism due to dysfunctional NADPH oxidase, either because of defective cytochrome [MIM*233710 and MIM*233690] or other specific factor deficiencies [MIM*233700 and MIM*306400]. As a result there is an increased susceptibility to severe infection by catalase-positive microorganisms; inheritance is usually autosomal recessive or X-linked.

granulomatous disease

(1) A nonspecific term for any disease characterised by multiple granulomas.
(2) Chronic granulomatous disease, see there.

Granulomatous disease

Characterized by growth of tiny blood vessels and connective tissue.
References in periodicals archive ?
Leprosy is a chronic granulomatous disease of the peripheral nerves and superficial tissues that is caused by Mycobacterium leprae, an acid-fast bacillus (1).
Posaconazole as salvage therapy in patients with chronic granulomatous disease and invasive filamentous fungal infection.
Melkersson-Rosenthal syndrome is a systemic neurological granulomatous disease which is relatively rare and has an unknown etiology.
In certain parts of USA fungal granulomas (histoplasmosis) are also to be kept in mind besides other granulomatous diseases like sarcoidosis, Wegener's granulomatosis, etc.
Susceptibility to mycobacterial infections in children with X-linked chronic granulomatous disease.
Investigators at the National Institutes of Health have observed that the survival rate of people with a rare immunodeficiency disease called chronic granulomatous disease (CGD) is greatly improved when even very low levels of microbe-killing molecules are present.
MRS is a systemic neuro-mucocutaneous granulomatous disease and is characterized by a triad, which includes orofacial edema, peripheral facial paralysis and lingua plicata.
Introduction: Pseudomonas aeruginosa (PA) is a common nosocomial pathogen primarily affecting immunodeficient individuals and in genetically susceptible diseases such as Cystic Fibrosis and Chronic Granulomatous Disease.
Introduction: Sarcoidosis is a chronic inflammatory multi-systemic granulomatous disease.
13) Granulomatous disease is deemed to be more resistant to treatment and may differ in its response to rituximab.

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