granulomatosis siderotica

granulomatosis /gran·u·lo·ma·to·sis/ (gran″u-lo″mah-to´sis) the formation of multiple granulomas.

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eosinophilic granulomatosis  Langerhans cell histiocytosis.

Langerhans cell granulomatosis  see under histiocytosis.

granulomatosis sidero´tica  a condition in which brownish nodules are seen in the enlarged spleen.

Wegener's granulomatosis  a progressive disease, with granulomatous lesions of the respiratory tract, focal necrotizing arteriolitis and, finally, widespread inflammation of all organs of the body.

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granulomatosis sid·e·rot·i·ca (sd-rt-k)

n.

Granulomatosis in which firm brown nodules that contain iron are present in an enlarged spleen.

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granulomatosis [gran″u-lo″mah-to´sis]

any condition involving the formation of multiple granulomas.

allergic granulomatosis churg-strauss syndrome.

eosinophilic granulomatosis Langerhans cell histiocytosis.

Langerhans cell granulomatosis Langerhans cell histiocytosis.

lymphomatoid granulomatosis a multisystem disease involving predominantly the lungs, skin, central nervous system, and kidneys, caused by invasion and destruction of vessels by atypical lymphoreticular cells. Many affected patients develop frank lymphoma. It usually affects males, and the most frequent presenting symptoms are cough, shortness of breath, and chest pain. Extrapulmonary manifestations are common, with skin lesions being present in many cases.

granulomatosis sidero´tica a condition in which brownish nodules are seen in the enlarged spleen.

Wegener's granulomatosis a multisystem disease chiefly affecting males, characterized by necrotizing granulomatous vasculitis involving the upper and lower respiratory tracts, glomerulonephritis, and variable degrees of systemic, small vessel vasculitis, which is generally considered to represent an aberrant hypersensitivity reaction to an unknown antigen.