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graft-versus-tumor |
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graft-versus-tumor Immunology An immune response to a graft recipient's tumor cells by a donor's transplanted immune cells in the BM or peripheral blood. See Graft-versus-host disease. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| The realization that the curative potential of any stem cell transplantation was largely the result of a graft-versus-tumor effect1-3 has led to wider use of reduced intensity or nonmyeloablative conditioning in preparation for allogeneic SCT during the past few years. Patients with rapidly advancing metastatic disease, who would be unlikely to live long enough for the generation of a graft-versus-tumor effect, would not benefit from such therapy. The study suggests the researchers turned the graft-versus-host reaction to some patients' advantage, making it a graft-versus-tumor response. |
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