CD40LG

(redirected from gp39)

CD40LG

A gene on chromosome Xq26 that encodes of a protein expressed on the surface of T cells which regulates B-cell function by binding CD40 to the B-cell surface. CD40LG is critical for immunoglobulin class switching. 

Molecular pathology
A defect in CD40LG is associated with hyper IgM syndrome due to an inability to undergo class switch.
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Tenders are invited for Provision of Mrc-15-011-Mt - Marc Gp39 Locomotives Overhaul.
Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40.
IDEC-131 targets the CD40 ligand (also known as gp39 or CD154) that is found primarily on activated T cells.
These corporate partnerships targeting immune cell receptors -- B7 with Mitsubishi Chemical, CD23 with Seikagaku Corporation and gp39 with Eisai Co.
Tenders are invited for MRC-15-011-MT - MARC GP39 Locomotives Overhaul
Tenders are invited for - MARC GP39 Locomotives Overhaul
The two companies will focus on developing humanized and PRIMATIZED antibodies against the gp39 antigen.
In addition, we strengthened our product portfolio by licensing research from Dartmouth Medical School on gp39, a receptor that is closely involved in controlling antibody production and inflammation.