CD40LG

(redirected from gp39)

CD40LG

A gene on chromosome Xq26 that encodes of a protein expressed on the surface of T cells which regulates B-cell function by binding CD40 to the B-cell surface. CD40LG is critical for immunoglobulin class switching. 

Molecular pathology
A defect in CD40LG is associated with hyper IgM syndrome due to an inability to undergo class switch.
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Tenders are invited for Provision of Mrc-15-011-Mt - Marc Gp39 Locomotives Overhaul.
Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40.
IDEC-131 targets the CD40 ligand (also known as gp39 or CD154) that is found primarily on activated T cells.
Tenders are invited for MRC-15-011-MT - MARC GP39 Locomotives Overhaul