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gp120 |
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gp120 HIV A 120 kD glycoprotein on the surface of HIV-1, which binds to cells–T cells, macrophages at the CD4 receptor. See AIDS, AIDS vaccine, HIV. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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However the best new drugs to emerge in the coming decade are likely to be members of new drug classes such as the several entry inhibitors (EIs)--CCR5 (R5), CXCR4 (X4), gp120, and fusion inhibitors--and possibly even newer approaches such as integrase, budding, and maturation inhibitors. Now, close inspection of the virus shows that seven of the people have a form of HIV with rare mutations in the gene encoding a glycoprotein called gp120 in the virus' outer surface. Human Milk Glycosaminoglycans Inhibit HIV Glycoprotein gp120 Binding to Its Host Cell CD4 Receptor," J Nutr 125:419-424. |
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