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gossypol

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gossypol /gos·sy·pol/ (gos´ĭ-pol) a toxin found in cottonseed and detoxified by heating; it has male antifertility properties, apparently having its effects in the seminiferous tubules.
gos·sy·pol (gs-pôl, -pl)
n.
A toxic pigment obtained from cottonseed oil and detoxified by heating, shown to inhibit sperm production.

gossypol (gäˑ·s·pōl),
n Latin name:
Gossypium hirsutum; parts used: stalks, roots, seeds; uses: contraceptive, dysmenorrhea, labor inducer; precautions: pregnancy, lactation, children; patients with kidney and liver disease; can cause cardiac failure, nausea, diarrhea, muscle weakness, and paralysis. Also called
American upland cotton and
cotton.

gossypol
toxic phenolic pigment in the glands of seeds of gossypium spp.


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Seed processors remove gossypol from cottonseed oil.
Moths developed on cotton will contain gossypol, a chemical found in cotton, in its system, says J.
In the 1970s, a trial involving more than 8,000 Chinese men who were given gossypol showed that the drug was well tolerated by most; however up to 10% of users had undesirable side effects, including hypokalemia and irreversibility of the contraceptive effect.
 
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